Endocrine Abstracts

The aim of this study was to compare metabolic profile in hypertensive obese and lean subjects. The study population consisted of 76 patients. We measured fasting glucose and insulin levels, triglycerides, total, LDL and HDL cholesterol. We also estimated the BMI, WHR, systolic (SBP) and diastolic blood pressure (DBP). We used WHO criteria for abdominal obesity (WHR>0.90 men, >0.85 women), and WHO criteria for diagnosing the metabolic syndrome (triglyceride>1.7 mmo...

Background: Serum paraoxonase-1 (PON-1) activity is decreased in clinical conditions associated with low high density-cholesterol (HDL-C), increased lipid peroxidation and low-grade chronic inflammation such as in type 2 diabetes mellitus (T2DM). Although many studies have shown that some poly unsaturated fatty acids (PUFA) modulate cardiovascular risk in T2DM, until now there is no data about the association of any fatty acid (FA) with PON-1 activity. This study aims to inves...

Adrenocortical carcinoma (ACC) is rare and aggressive malignancy with poor prognosis. Patients present with hormone excess or a local mass effect, or incidentally. ACC has undergone metastatic spread in 40–70% of patients at the time of diagnosis. Surgical removal is treatment of choice. Standard chemotherapy with mitotane has limited efficacy.The aim of this paper is to present the results of single tertiary center for diagnosis and treatment of AC...

Bacground: In type 2 diabetes mellitus (T2DM), the level of polyunsaturated fatty acids (PUFA), is usually decreased, and could be accused for metabolic disturbance, chronic inflammation, and accelerated atherosclerosis. The aim of this study was to determine if there is any relationship between composition of plasma phospholipids PUFAs and parameters of metabolic syndrome.Methods: The study was cross-sectional. Fifteen T2DM patients 63.22±7.20, BMI...

Criteria to define biochemical remission of acromegaly following surgery have changed over the years, but still the controversy about current consensus exists. We assessed seventy newly diagnosed patients with acromegaly (43 females and 27 males, mean age 46.9±1.4 years, range 17–66 yrs) 8 weeks after transsphenoidal pituitary adenomectomy done by the same neursurgeon. Current consensus criteria were used to define postoperative remission: glucose-suppressed (nadir) ...